Entropy guards pore

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Entropy guards pore

Entropy guards pore T he rapid fl uctuations of fl exible FG repeat–containing nucleoporins (FG Nups) form an entropic barrier to would-be entrants into the nuclear pore complex (NPC), according to Roderick Lim (University of Basel, Switzerland) and colleagues. FG Nups, which consist of large natively unfolded domains, are the pore’s gatekeepers—they keep out proteins that are not bound to tran...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2006

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.1741rr3